MyCardium AI Serves as Core Laboratory in Landmark NEJM Myocardial Infarction Trial

London, UK - October 2025

MyCardium AI is proud to announce its role as the Core Laboratory in the recently published NEJM study: Immediate or Deferred Nonculprit-Lesion PCI in Myocardial Infarction.

The trial investigated whether percutaneous coronary intervention (PCI) of nonculprit lesions should be performed immediately or deferred in patients with myocardial infarction. This study has significant implications for clinical decision-making in acute coronary syndromes and for optimising patient outcomes.

MyCardium AI’s Contribution

As the Core Lab, MyCardium AI performed centralised cardiac MRI analysis. Our 1CMR Pro imaging software, FDA 510(k) cleared and CE class 1b marked, enabled automated, reproducible, quantification, ensuring data consistency and reducing bias.

Why This Matters

• Highlights the easability of AI-enabled cardiac MRI analysis in large, multicentre cardiovascular trials.
• Reinforces the role of MyCardium AI in delivering reliable, centralised imaging data that supports clinical decision-making and research integrity.

We would like to congratulate Dr Robin Nijveldt and his team for this outstanding achievement, and for partnering with MyCardium AI Core Lab for the MRI analysis of this study.

By combining AI-driven quantification with expert oversight, MyCardium AI ensures objective and reproducible results, vital for the success of large-scale cardiovascular trials.

“We’re delighted that our platform and team contributed to this pivotal research,” said Dr. George Thornton, Core Lab Chief Medical Officer, MyCardium AI.

“It reflects how technology-enabled imaging analytics can accelerate clinical discovery and deliver deeper insights into cardiovascular health.”

MyCardium AI continues to support academic indusrty and clinical partners worldwide by providing AI-enabled MRI and echocardiography analysis, helping drive innovation, regulatory compliance, and evidence-based patient care.

Read the full study in the New England Journal of Medicine:

Immediate or Deferred Nonculprit-Lesion PCI in Myocardial Infarction

Robin Nijveldt - Professor of Cardiovascular Imaging